COMPARISON OF LUMBAR INTERLAMINAR EPIDURAL STEROID VERSUS CAUDAL EPIDURAL STEROID IN TREATMENT OF LUMBAR SPINAL STENOSIS

Authors

  • SY KHAN Department of Trauma and Orthopedics, Mayo Hospital Lahore, Pakistan
  • M AKRAM Department of Trauma and Orthopedics, Mayo Hospital Lahore, Pakistan

DOI:

https://doi.org/10.54112/pjicm.v5i02.156

Keywords:

Lumbar Spinal Stenosis, Epidural Steroid Injection, Interlaminar Approach, Caudal Approach, Oswestry Disability Index, Numeric Pain Rating Scale

Abstract

Background: Lumbar spinal stenosis (LSS) is a common cause of low back pain and disability in adults. Epidural steroid injections are frequently used for symptomatic relief, but the optimal approach remains debated. Objective: To compare clinical outcomes between caudal and interlaminar epidural steroid injections in patients with lumbar spinal stenosis. Study Design: Randomized controlled trial. Setting: Orthopedic Unit I, Mayo Hospital, Lahore, Pakistan. Duration of Study: 02-March-2024 to 02-September-2024. Methods: A total of 416 patients with clinically and radiologically confirmed LSS (Lee Grade 1–3 on MRI) were randomly allocated into two groups. Group A received fluoroscopically-guided interlaminar epidural steroid injections at the L2–L3 level, while Group B received fluoroscopically-guided caudal epidural steroid injections. The Oswestry Disability Index (ODI) and Numeric Pain Rating Scale (NPRS) were assessed at baseline and at 12 weeks post-intervention. Results: At the 12-week follow-up, Group A demonstrated significantly lower mean NPRS scores (2.65 ± 1.084) compared to Group B (3.25 ± 1.332; p = 0.0001). Functional improvement was also greater in Group A, with a lower mean ODI score (13.97 ± 2.045) versus Group B (15.91 ± 3.277; p = 0.0001). Conclusion: Interlaminar epidural steroid injection provided superior pain relief and functional improvement compared to caudal epidural steroid injection in patients with lumbar spinal stenosis.

References

Kwon JW, Moon SH, Park SY, Park SJ, Park SR, Suk KS, et al. Lumbar spinal stenosis: review update 2022. Asian Spine Journal. 2022;16(5):789–798. https://doi.org/10.31616/asj.2022.0366

Jensen RK, Jensen TS, Koes B, Hartvigsen J. Prevalence of lumbar spinal stenosis in general and clinical populations: a systematic review and meta-analysis. European Spine Journal. 2020;29(9):2143–2163. https://doi.org/10.1007/s00586-020-06339-1

Walter KL, O’Toole JE. Lumbar spinal stenosis. JAMA. 2022;328(3):310. https://doi.org/10.1001/jama.2022.6137

Lee BH, Moon SH, Suk KS, Kim HS, Yang JH, Lee HM. Lumbar spinal stenosis: pathophysiology and treatment principle: a narrative review. Asian Spine Journal. 2020;14(5):682–693. https://doi.org/10.31616/asj.2020.0472

Hennemann S, Abreu MR. Degenerative lumbar spinal stenosis. Revista Brasileira de Ortopedia. 2021;56(1):9–17. https://doi.org/10.1055/s-0040-1712490

Jensen RK, Lauridsen HH, Andresen AD, Mieritz RM, Schiøttz-Christensen B, Vach W. Diagnostic screening for lumbar spinal stenosis. Clinical Epidemiology. 2020;12:891–905. https://doi.org/10.2147/CLEP.S263646

Yabuki S, Fukumori N, Takegami M, Onishi Y, Otani K, Sekiguchi M, et al. Prevalence of lumbar spinal stenosis, using the diagnostic support tool, and correlated factors in Japan: a population-based study. Journal of Orthopaedic Science. 2013;18(6):893–900. https://doi.org/10.1007/s00776-013-0455-5

Lee BH, Moon SH, Suk KS, Kim HS, Yang JH, Lee HM. Lumbar spinal stenosis: pathophysiology and treatment principle: a narrative review. Asian Spine Journal. 2020;14(5):682–693. https://doi.org/10.31616/asj.2020.0472

Chen X, Zheng Z, Lin J. Clinical effectiveness of conservative treatments on lumbar spinal stenosis: a network meta-analysis. Frontiers in Pharmacology. 2022;13:859296. https://doi.org/10.3389/fphar.2022.859296 .

Do KH, Kim TH, Chang MC. Effects of interlaminar epidural steroid injection in patients with moderate to severe lumbar central spinal stenosis: a prospective study. Annals of Palliative Medicine. 2020;9(2):163–168. https://doi.org/10.21037/apm.2020.02.20

Kwak SG, Choo YJ, Kwak S, Chang MC. Effectiveness of transforaminal, interlaminar, and caudal epidural injections in lumbosacral disc herniation: a systematic review and network meta-analysis. Pain Physician. 2023;26(2):113–123.

Hasoon J, Viswanath O, Orhurhu V, Abd-Elsayed A. Caudal epidural steroid injections: a retrospective pilot study of safety and patient-reported outcomes. Orthopedic Reviews. 2025;17:134102. https://doi.org/10.52965/001c.134102

Nagpal AS, Vu TN, Gill B, Conger A, McCormick ZL, Duszynski B, et al. Systematic review of the effectiveness of caudal epidural steroid injections in the treatment of chronic low back or radicular pain. Interventional Pain Medicine. 2022;1(4):100149. https://doi.org/10.1016/j.inpm.2022.100149

Manchikanti L, Falco FJ, Pampati V, Hirsch JA. Lumbar interlaminar epidural injections are superior to caudal epidural injections in managing lumbar central spinal stenosis. Pain Physician. 2014;17(6):E691–E702. https://doi.org/10.36076/ppj.2014/17/E691

Manchikanti L, Cash KA, McManus CD, Damron KS, Pampati V, Falco FJ. A randomized, double-blind controlled trial of lumbar interlaminar epidural injections in central spinal stenosis: 2-year follow-up. Pain Physician. 2015;18(1):79–92. https://doi.org/10.36076/ppj/2015.18.79

Manchikanti L, Pampati V, Benyamin RM, Boswell MV. Analysis of efficacy differences between caudal and lumbar interlaminar epidural injections in chronic lumbar axial discogenic pain: local anesthetic alone vs. local combined with steroids. International Journal of Medical Sciences. 2015;12(3):214–222. https://doi.org/10.7150/ijms.10870

Beyaz SG. Comparação das técnicas transforaminal e interlaminar de injeções epidurais de esteroides para o tratamento de dor lombar crônica [Comparison of transforaminal and interlaminar epidural steroid injections for the treatment of chronic lumbar pain]. Revista Brasileira de Anestesiologia. 2017;67(1):21–27. https://doi.org/10.1016/j.bjan.2016.09.010.

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Published

2025-07-14

How to Cite

KHAN , S., & AKRAM , M. (2025). COMPARISON OF LUMBAR INTERLAMINAR EPIDURAL STEROID VERSUS CAUDAL EPIDURAL STEROID IN TREATMENT OF LUMBAR SPINAL STENOSIS. Pakistan Journal of Intensive Care Medicine, 5(02), 156. https://doi.org/10.54112/pjicm.v5i02.156

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Original Research Articles